2025
Late-Stage Amination of Peptides on the Solid Phase
Strand-Swapped SH3 Domain Dimer with Superoxide Dismutase Activity
2024
Thermostable WW Domain Scaffold to Design Functional β-Sheet Miniproteins
C. Lindner, A. Friemel, N. Schwegler, L. Timmermann, T. L. Pham, V. Reusche, M. Kovermann*, F. Thomas*, J. Am. Chem. Soc. 2024, 146, 24, 16590–16600.
Design of Functional Globular β-Sheet Miniproteins
Bioconjugation in Materials Science
Peptide Boronic Acids by Late-Stage Hydroboration on the Solid Phase
M. Werner, J. Brinkhofer, L. Hammermüller, T. Heim, T. L. Pham, J. Huber, C. Klein*, F. Thomas*, Adv. Sci. 2024, 202400640.
Multimaterial 3D Laser Printing of Cell-Adhesive and Cell-Repellent Hydrogels
Brought to Light: A Fluorogenic Probe to Monitor Immunosuppressants
Relationship of Thermostability and Binding Affinity in Metal-binding WW-Domain Minireceptors
2023
Rapid On-Resin N-Formylation of Peptides as One-Pot Reaction
An Engineered β-Hairpin Peptide Forming Thermostable Complexes with Zn(II), Ni(II), and Cu(II) through a His3 Site
α-Helix and Coiled-Coil Peptide Nanomaterials
HAV-Peptides Attached to Colloidal Probes Faithfully Detect E-cadherins Displayed on Living Cells
2022
Identification of novel functional mini‐receptors by combinatorial screening of split‐WW domains
Switchable Zinc(II)-Responsive Globular β-Sheet Peptide
Late-Stage Functionalization of Peptides on the Solid Phase by an Iodination-Substitution Approach
The CSY-protecting group in the microwave-assisted synthesis of aggregation-prone peptides
2021
Falsch gewickelt. Wenn Proteine krank machen
Ganz ohne Glas
Hexafluoroisopropanol as solvent and promotor in the Paal-Knorr synthesis of N-substituted diaryl pyrroles
Effect of Methionine Sulfoxide on the Synthesis and Purification of Aggregation‐Prone Peptides
2007-2020
Neues zur Synthese von Aminoboronsäuren
De Novo Designed α-Helical Coiled-Coil Peptides as Scaffolds for Chemical Reactions
Kinetic studies on strand displacement in de novo designed parallel heterodimeric coiled coils
Controlling the Assembly of Coiled-Coil Peptide Nanotubes
A Set of de novo Designed Parallel Heterodimeric Coiled Coils with Quantified Dissociation Constants in the Micromolar to Sub-nanomolar Regime
Automated Fmoc-Based Solid-Phase Synthesis of Peptide Thioesters with Self-Purification Effect and Application in the Construction of Immobilized SH3-Domains
Je später, desto lieber: C(sp3)‐H‐Hydroxylierung
Decoration of Coiled-Coil Peptides with N-Cysteine Peptide Thioesters as Cyclic Peptide Precursors Using CuAAC Click Reaction
Carbon Nanotubes Encapsulated in Coiled-Coil Peptide Barrels
Modular Design of Self-assembling Peptide-based Nanotubes
Fmoc-based peptide thioester synthesis with self-purifying effect: heading to native chemical ligation in parallel formats
Chemical Control of Biomolecular Interaction Modules
Guiding Biomolecular Interactions in Cells Using de Novo Protein-Protein Interfaces
De Novo-Designed α-Helical Barrels as Receptors for Small Molecules
Conformational Dynamics of Asparagine at Coiled-Coil Interfaces
Accessibility, Reactivity and Selectivity of Side Chains within a Channel of de novo Peptide Assembly
9-Fluorenylmethoxycarbonyl-Based Solid-Phase Synthesis of Peptide α-Thioesters
Solid-Phase Synthesis of Peptide Thioesters with Self-Purification